Shanghai Sonyt Biotechnology Co., Ltd. is one of the leading manufacturers and suppliers of biotin-oxytocin in China, also supports custom service. Welcome to wholesale bulk high quality biotin-oxytocin from our factory. Contact us for more details.
| Biotin-Oxytocin | |
| Biotin-labeled oxytocin is a modified oxytocin that retains full receptor binding activity. Biotin tag is site-specifically conjugated to the N-terminus of native oxytocin, enabling receptor tracing, affinity purification, immunoassay and other applications via the biotin-streptavidin system, while fully retaining the receptor binding and biological activity of oxytocin. Applied in oxytocin receptor localization, neuroendocrine pathway, receptor-ligand interaction and other research. | |
| 95% / 98% / 99% | |
| Free oxytocin molecular weight 1007.19 Da | |
| N-terminal site-specific biotin labeling, disulfide cyclization, C-terminal amidation |
| Function Tags (comma-separated) | ||||||||
| Biotin-Oxytocin | Oxytocin nonapeptide backbone + biotin tag + linker, disulfide cyclized | Large modified peptide, no precise small-molecule formula; subject to actual batch MS | - | ~1230 (including biotin and linker) | N-terminal site-specific biotin labeling |
| Long-term Storage Conditions | Short-term Storage Conditions | ||||
| PEP-BOT001 | Store at -20℃, strictly protected from light, sealed and dry, aliquoted. **Strictly prohibited from strong reducing agents** | Solid powder stable for 1 year at 2-8℃ sealed & dry; prepare aqueous solutions freshly before use | Stable for 72 h at 4℃ in dark; stable for 1 month at -20℃ in aliquots. **Good water solubility, freely soluble in water and physiological buffer**. Disulfide bridge highly sensitive to strong reducing agents and prone to cleavage. Avoid free biotin competition in the system | Stable for 3 years at -20℃ under dry & dark conditions |
| Applicable Research Areas (comma-separated) | ||||
| PEP-BOT001 | Site-specific biotin-labeled oxytocin with full receptor activity for receptor tracing and affinity purification | Biotin-labeled oxytocin introduces a flexible linker at the N-terminus of native oxytocin for site-specific biotin conjugation, maximally retaining the spatial conformation and receptor binding affinity of oxytocin. It specifically binds to the oxytocin receptor (OXTR) and mediates classic biological effects such as uterine contraction and lactation reflex. The biotin tag binds with high affinity to streptavidin, avidin and other proteins, and is widely used in immunohistochemical localization of oxytocin receptors, receptor affinity purification, ligand binding kinetics analysis, receptor endocytosis tracing and other experiments. It is an important tool molecule for neuroendocrine research and receptor pharmacology analysis. | Oxytocin Receptor (OXTR); Biotin-streptavidin system; Uterine smooth muscle contraction pathway |
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